{"id":922,"date":"2023-08-16T16:23:57","date_gmt":"2023-08-16T16:23:57","guid":{"rendered":"https:\/\/growersforbiotechnology.org\/?p=922"},"modified":"2023-08-16T16:25:50","modified_gmt":"2023-08-16T16:25:50","slug":"5x-increase-in-rice-yields-new-crispr-created-variety-could-help-fight-fungal-pandemic-decimating-worlds-rice-crop","status":"publish","type":"post","link":"https:\/\/growersforbiotechnology.org\/2023\/08\/16\/5x-increase-in-rice-yields-new-crispr-created-variety-could-help-fight-fungal-pandemic-decimating-worlds-rice-crop\/","title":{"rendered":"5x increase in rice yields? New CRISPR-created variety could help fight fungal pandemic decimating world\u2019s rice crop"},"content":{"rendered":"

Thanks to CRISPR, farmers may finally have a good defense against rice blast, a fungal disease so devastating, it\u2019s known as the \u201ccancer of rice<\/a>.\u201d<\/p>\n

The challenge<\/strong><\/h3>\n

Rice provides\u00a0more than 20%<\/a>\u00a0of the world\u2019s calories, but every year, rice blast wipes out\u00a010-30%<\/a>\u00a0of the world\u2019s rice crops, making it a major threat to both global food security and economies that depend on rice production.<\/p>\n

\u201cBlast is the most serious disease of plants in the world because it affects virtually all growing regions of rice and also because rice is a huge crop,\u201d\u00a0said<\/a>\u00a0Pamela Ronald, a distinguished professor in the Department of Plant Pathology at UC Davis.<\/p>\n

<\/p>\n

Spores of rice blast fungus. Credit: USDA Forest Service via CC0-1.0<\/em><\/p>\n

 <\/p>\n

\u201cThe results from this study could help shore up food supply in the future.\u201d\u00a0<\/em> \u2014Jenny Mortimer<\/p><\/blockquote>\n

 <\/p>\n

What\u2019s new?<\/strong><\/h3>\n

Ronald and an international team of researchers have now found a way to use CRISPR to make plants resistant to rice blast. In small field trials, their gene-edited rice plants yielded five times as much rice as controls when challenged with the fungus that causes blast.<\/p>\n

\u201cRice crops with higher yields are needed to meet growing global demand, and the results from this study could help shore up food supply in the future,\u201d\u00a0said<\/a>\u00a0study co-author Jenny Mortimer from the University of Adelaide.<\/p>\n

The idea<\/strong><\/h3>\n

During a rice blast infection, lesions \u2014 spots of dead cells \u2014 form on the parts of the plant above the ground. Unless a farmer treats the infection early with expensive fungicides, these lesions spread and merge until the entire plant is dead.<\/p>\n

Just like we have an immune system to protect us from diseases,\u00a0rice plants<\/a>\u00a0have one, too, but while a rice blast infection\u00a0can<\/em>\u00a0trigger an immune response<\/a>, the plant\u2019s natural defenses are usually overwhelmed by the fungus.<\/p>\n

Enter: \u201clesion mimic mutants.\u201d<\/p>\n

 <\/p>\n

Genetic sequencing led to the discovery of a mutant that conferred protection against infections.<\/em><\/p><\/blockquote>\n

 <\/p>\n

These genetic mutations cause plants to display the same patches of dead cells present during an infection, despite the plant being infection-free. As a result, their immune systems swing into action, killing the cells around the lesions to prevent the \u201cinfection\u201d from spreading.<\/p>\n

<\/p>\n

A typical eye-shaped lesion of rice blast disease on a U.S. rice cultivar inoculated with Magnaporthe grisea. Credit: Yulin Jia via USDA ARS and CC0-1.0<\/em><\/p>\n

 <\/p>\n

While working in Ronald\u2019s lab, study co-lead author Guotian Li \u2014 now at Huazhong Agricultural University \u2014 sequenced more than 3,200 rice plant strains, leading to the discovery of a mutant that conferred protection against bacterial infections.<\/p>\n

Plants with the natural mutation were small and didn\u2019t yield much rice, but the researchers were able to identify the mutant gene, which they call RBL1 (resistance to blast1).<\/p>\n

Using\u00a0CRISPR<\/a>\u00a0and other techniques, they\u2019ve now created a line of rice plants with a version of the RBL1 mutation that makes them resistant to\u00a0three\u00a0<\/em>bacterial and fungal infections \u2014 including rice blast \u2014 while also producing good yields.<\/p>\n

Enter: \u201clesion mimic mutants.\u201d<\/p>\n

 <\/p>\n

\u201cWe\u2019re hoping that people can \u2026 edit them to get a nice balance between resistance and high yield.\u201d <\/em>\u2014Pamela Ronald<\/p><\/blockquote>\n

 <\/p>\n

Looking ahead<\/strong><\/h3>\n

Larger field trials are needed to confirm the study\u2019s results, and the researchers also plan to try recreating their success in other varieties of rice \u2014 the\u00a0variety they used<\/a>\u00a0grows fast, making it useful for studies, but it isn\u2019t commonly grown for food.<\/p>\n

The scientists are hopeful their research will inspire others to consider how CRISPR, combined with data on natural genetic diversity, could be used to create better crops.<\/p>\n

\u201cA lot of these lesion mimic mutants have been discovered and sort of put aside because they have low yield,\u201d said Ronald. \u201cWe\u2019re hoping that people can go look at some of these and see if they can edit them to get a nice balance between resistance and high yield.\u201d<\/p>\n

\n

Kristin Houser is a staff writer at Freethink, where she covers science and tech. Her written work has appeared in Business Insider, NBC News, and the World Economic Forum\u2019s Agenda, among other publications. Follow Kristin on Twitter\u00a0@KristinJHouser<\/a><\/strong><\/p>\n

A version of this article was originally posted at Freethink and has been reposted here with permission. Any reposting should credit the original author and provide links to both the GLP and the original article. Find Freethink on Twitter\u00a0@freethinkmedia<\/a><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"

Thanks to CRISPR, farmers may finally have a good defense against rice blast, a fungal disease so devastating, it\u2019s known as the \u201ccancer of rice.\u201d The challenge Rice provides\u00a0more than 20%\u00a0of the world\u2019s calories, but every year, rice blast wipes out\u00a010-30%\u00a0of the world\u2019s rice crops, making it a major threat to both global food security…<\/p>\n","protected":false},"author":1,"featured_media":923,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4],"tags":[9],"yoast_head":"\n5x increase in rice yields? 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